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Translational Medicine / 转化医学EGFR Exon 20 Insertion Lung Cancer

John Heymach

MD, PhD

🏢MD Anderson Cancer Center🌐USA

Chair, Department of Thoracic/Head and Neck Medical Oncology

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Key Contributions

👥Biography 个人简介

John Heymach has led the clinical development of poziotinib for EGFR and HER2 exon 20 insertion mutations. His translational research program at MD Anderson integrates structural biology with drug design for uncommon EGFR variants. He has pioneered combination strategies to overcome resistance in exon 20 mutant tumors.

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🧪Research Fields 研究领域

EGFR exon 20 insertions
Poziotinib
Thoracic oncology
Drug resistance
Precision oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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