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Translational Medicine / 转化医学LAG-3 Biology, Next Generation Checkpoints

Heloise Bhatt

PhD

🏢Bristol Myers Squibb🌐USA

Immunology Researcher

18
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Key Papers
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Key Contributions

👥Biography 个人简介

Heloise Bhatt has contributed to the biology of LAG-3 (Lymphocyte Activation Gene-3) — a second-generation immune checkpoint whose blockade has now been validated in combination with anti-PD-1. The RELATIVITY-047 trial established relatlimab (anti-LAG-3) plus nivolumab as a superior first-line melanoma treatment compared to nivolumab alone, marking the first approval of a combination checkpoint blockade regimen beyond ipilimumab-nivolumab.

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🧪Research Fields 研究领域

LAG-3 relatlimab
LAG-3 biology
anti-LAG-3 cancer therapy
next generation checkpoint combinations
RELATIVITY-047

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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