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Translational Medicine / 转化医学HER2 Exon 20 NSCLC

Helena Yu

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Associate Attending Physician

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Key Papers
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Key Contributions

👥Biography 个人简介

Helena Yu investigates HER2 exon 20 insertion mutations in NSCLC and has contributed to pivotal trials of trastuzumab deruxtecan and emerging HER2-selective tyrosine kinase inhibitors. Her work defines molecular subsets and resistance mechanisms within HER2-altered NSCLC. She leads early-phase clinical development for novel HER2 agents.

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🧪Research Fields 研究领域

HER2 exon 20 insertion NSCLC
T-DXd HER2 lung cancer
HER2 TKIs
HER2 resistance NSCLC
early-phase lung trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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