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Translational Medicine / 转化医学NSCLC, EGFR Exon 20 Insertions

Helena Yu

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Assistant Attending Physician, Thoracic Oncology

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Key Contributions

👥Biography 个人简介

Helena Yu is a leading expert on atypical EGFR mutations in NSCLC, particularly exon 20 insertion mutations that were historically resistant to standard EGFR inhibitors. She has been instrumental in characterizing the clinical activity of amivantamab and mobocertinib in this previously difficult-to-treat population. Her research encompasses the molecular biology of insertion mutations and strategies to improve targeted therapy outcomes. She actively participates in multi-institutional consortia studying rare EGFR variants.

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🧪Research Fields 研究领域

EGFR exon 20 insertions
amivantamab
mobocertinib
atypical EGFR mutations
bispecific antibodies EGFR/MET

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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