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Translational Medicine / 转化医学Brain Metastasis, Targeted Therapy CNS

Helena Yu

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Assistant Attending Physician

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Key Contributions

👥Biography 个人简介

Dr. Helena Yu is a thoracic oncologist at MSKCC specializing in CNS management of EGFR and ALK-positive lung cancer. She has contributed to clinical research on osimertinib CNS efficacy and led trials evaluating lorlatinib's activity in ALK-positive NSCLC with brain metastases. Her work has helped define the sequencing of CNS-penetrant TKIs to delay or avoid radiation in EGFR/ALK-driven brain disease.

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🧪Research Fields 研究领域

EGFR TKI CNS penetration
ALK inhibitor brain metastases
osimertinib brain activity
lorlatinib CNS efficacy
NSCLC brain metastases targeted therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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