Hedy Kindler
海蒂·金德勒
MD
Professor of Medicine and Director, Mesothelioma Program内科学教授兼间皮瘤项目主任
👥Biography 个人简介
Hedy Kindler is a leading mesothelioma medical oncologist at the University of Chicago, known for her pivotal role in bevacizumab-based combination trials and peritoneal mesothelioma research. She has led numerous landmark cooperative group trials shaping modern systemic therapy for mesothelioma.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Antiangiogenic Therapy
Led the MAPS trial investigating bevacizumab plus cisplatin/pemetrexed in pleural mesothelioma, establishing a new first-line standard of care in Europe.
Peritoneal Mesothelioma
Conducted pivotal studies on peritoneal mesothelioma epidemiology and systemic therapy, improving outcomes for this rare and poorly understood disease variant.
Clinical Trial Leadership
Led CALGB and Alliance cooperative group mesothelioma trials, generating high-level evidence that underpins current NCCN and ESMO treatment guidelines.
Representative Works 代表性著作
Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS)
Lancet (2016)
Phase III trial showing bevacizumab addition improved overall survival in mesothelioma, establishing a new first-line regimen.
Phase II trial of bevacizumab in patients with malignant mesothelioma
Journal of Clinical Oncology (2001)
First major evaluation of VEGF inhibition in mesothelioma, demonstrating the rationale for antiangiogenic strategies.
Second-line pemetrexed in malignant pleural mesothelioma
Journal of Thoracic Oncology (2011)
Defined the role of pemetrexed retreatment, informing sequencing decisions in recurrent mesothelioma management.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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