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Translational Medicine / 转化医学Lung Cancer, First-Line Immunotherapy

Hatim Husain

MD

🏢UC San Diego Moores Cancer Center🌐USA

Associate Professor of Medicine

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Key Contributions

👥Biography 个人简介

Hatim Husain contributed to KEYNOTE-407 establishing pembrolizumab plus chemotherapy for squamous NSCLC and has expertise in liquid biopsy and ctDNA monitoring in the context of first-line immunotherapy for lung cancer. His translational research explores ctDNA dynamics as biomarkers of IO response and resistance, and he leads early-phase trials of novel IO combinations. Husain has been active in developing next-generation sequencing and molecular profiling approaches for NSCLC immunotherapy selection. His work bridges genomics with clinical immunotherapy outcomes in thoracic cancers.

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🧪Research Fields 研究领域

squamous versus non-squamous first-line IO
KEYNOTE-407 squamous NSCLC
pembrolizumab squamous first-line
NSCLC histology IO differences
first-line combination IO squamous

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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