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Translational Medicine / 转化医学H pylori, Gastric Cancer Biology

Masanori Hatakeyama

MD, PhD

🏢University of Tokyo🌐Japan

Professor, Graduate School of Medicine

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Key Papers
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Key Contributions

👥Biography 个人简介

Masanori Hatakeyama characterized the cagA bacterial oncoprotein of H pylori as a phosphotyrosine-dependent activator of SHP-2 signaling and established cagA as the first bacterial oncoprotein. His work at Tokyo has defined molecular mechanisms by which H pylori drives gastric carcinogenesis. His research bridges microbiology and cancer biology.

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🧪Research Fields 研究领域

cagA oncoprotein mechanism
SHP-2 signaling
gastric carcinogenesis
H pylori bacterial oncoprotein
EPIYA motifs

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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