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Translational Medicine / 转化医学Oncogene Discovery Nobel, Cancer Research Leadership

Harold Varmus

MD

🏢Weill Cornell Medicine🌐USA

Professor

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Key Contributions

👥Biography 个人简介

Harold Varmus shared the 1989 Nobel Prize in Physiology or Medicine with J. Michael Bishop for discovering that oncogenes — cancer-causing genes — originate from normal cellular genes (proto-oncogenes). This discovery that cancer arises from mutations in the body's own genes rather than from external cancer-causing agents was a conceptual revolution in cancer biology. His subsequent leadership as NCI Director and cancer research contributions have made him one of the most influential figures in 20th/21st century cancer science.

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🧪Research Fields 研究领域

src oncogene Nobel Prize cancer
proto-oncogene cancer origin
NCI cancer research leadership
lung cancer KRAS
cancer science policy NIH

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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