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Translational Medicine / 转化医学AMPK Signaling, Energy Sensing

D. Grahame Hardie

PhD

🏢University of Dundee🌐UK

Emeritus Professor of Cellular Signalling

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Key Contributions

👥Biography 个人简介

D. Grahame Hardie discovered and characterized AMP-activated protein kinase as a master sensor of cellular energy status. His decades of work established AMPK as a tumor suppressor and a key mediator of metformin action. He remains a foundational figure in metabolic signaling research.

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🧪Research Fields 研究领域

AMPK
energy metabolism
cell signaling
metformin
cancer metabolism

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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