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Translational Medicine / 转化医学Oncolytic Virus, CAVATAK Coxsackievirus

Hardev Pandha

MD, PhD, FRCP

🏢University of Surrey🌐UK

Professor of Medical Oncology

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👥Biography 个人简介

Hardev Pandha has developed coxsackievirus A21 (CAVATAK) as an oncolytic agent and led early-phase clinical trials in melanoma and bladder cancer, demonstrating activity through ICAM-1-mediated viral entry. His research has characterized the immune-stimulatory consequences of coxsackievirus oncolysis and explored combinations with pembrolizumab in phase I/II studies. He is a leading proponent of intravesical oncolytic virus therapy for bladder cancer.

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🧪Research Fields 研究领域

coxsackievirus A21 CAVATAK oncolytic
oncolytic virus prostate cancer
ICAM-1 targeted oncolytic virus
melanoma bladder oncolytic virus
combination oncolytic pembrolizumab

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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