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Translational Medicine / 转化医学Oncology Regulatory Science

Harald zur Hausen

哈拉尔德·楚尔·豪森

MD

🏢German Cancer Research Center (DKFZ), Heidelberg(德国癌症研究中心(DKFZ),海德堡)🌐Germany

Professor Emeritus; Former Scientific Director, DKFZ荣誉退休教授;德国癌症研究中心前科学主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Harald zur Hausen discovered that human papillomavirus (HPV) causes cervical cancer, earning the 2008 Nobel Prize in Physiology or Medicine. His discovery directly enabled development and regulatory approval of HPV vaccines that have transformed cervical cancer prevention globally.

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🧪Research Fields 研究领域

HPV Cancer DiscoveryHPV癌症发现
Viral Oncology病毒肿瘤学
Cancer Prevention癌症预防
Translational Regulatory Impact转化监管影响

🎓Key Contributions 主要贡献

HPV and Cervical Cancer Causation

Identified HPV 16 and HPV 18 as the causative agents of most cervical cancers, providing the biological foundation for preventive vaccines and reshaping cancer etiology research.

HPV Vaccine Development Enabling Science

Foundational HPV research directly enabled regulatory approval of Gardasil and Cervarix, vaccines that have dramatically reduced cervical cancer incidence worldwide.

Viral Oncology Research Leadership at DKFZ

As Scientific Director of DKFZ, built Germany's leading cancer research program, training generations of scientists and advancing translational cancer research standards.

Representative Works 代表性著作

[1]

A Papillomavirus DNA from a Cervical Carcinoma and Its Prevalence in Cancer Biopsy Samples

Proceedings of the National Academy of Sciences (1984)

Nobel Prize-generating discovery reporting isolation and characterization of HPV 18 from cervical carcinoma tissue.

[2]

Papillomaviruses Causing Cancer: Evasion from Host-Cell Control in Early Events in Carcinogenesis

Journal of the National Cancer Institute (2000)

Comprehensive review of HPV oncogenic mechanisms that guided vaccine antigen design and regulatory strategy.

[3]

Infections Causing Human Cancer

Wiley-VCH (Book) (2006)

Authoritative monograph on infectious causes of cancer, influencing international cancer prevention and regulatory policy.

🏆Awards & Recognition 奖项与荣誉

🏆Nobel Prize in Physiology or Medicine (2008)
🏆Robert Koch Prize
🏆Charles S. Mott Prize, General Motors Cancer Research Foundation
🏆William B. Coley Award for Distinguished Research in Basic and Tumor Immunology

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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