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Translational Medicine / 转化医学Radiation Biology, LET RBE Proton Therapy

Harald Paganetti

PhD

🏢Massachusetts General Hospital🌐USA

Professor, Department of Radiation Oncology

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Key Contributions

👥Biography 个人简介

Harald Paganetti is a leading authority on relative biological effectiveness (RBE) and LET in proton therapy. His work has clarified how RBE varies as a function of LET along the proton depth-dose profile, with implications for treatment planning and end-of-range toxicity. He has contributed to the RBE 1.1 convention debate and advocates for variable RBE models in proton treatment planning systems.

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🧪Research Fields 研究领域

relative biological effectiveness proton therapy
linear energy transfer proton
LET-dependent RBE variation
proton versus photon radiobiology
proton beam end-of-range RBE

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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