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Translational Medicine / 转化医学Lynch Syndrome, HNPCC

Hans Vasen

MD

🏢Leiden University Medical Center🌐Netherlands

Senior Investigator

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Key Papers
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Key Contributions

👥Biography 个人简介

Hans Vasen at LUMC is Europe's leading Lynch syndrome expert, having contributed to defining the clinical criteria (originally Amsterdam Criteria, later revised) for Lynch syndrome and establishing surveillance colonoscopy protocols that have dramatically reduced colorectal cancer mortality in Lynch families. His decades of longitudinal follow-up of Lynch syndrome kindreds has provided the evidence base for cancer risk estimates and prevention guidelines.

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🧪Research Fields 研究领域

Lynch syndrome
HNPCC surveillance
mismatch repair genes
colorectal cancer prevention Lynch
European Lynch guidelines

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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