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Translational Medicine / 转化医学KRAS G12C Later-Line Therapy

Jill Hallin

PhD

🏢Mirati Therapeutics🌐USA

Vice President, Translational Sciences

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Key Contributions

👥Biography 个人简介

Jill Hallin led the preclinical characterization of adagrasib (MRTX849) that established its pharmacologic properties favoring CNS penetration and combination potential. Her translational science work defined rational combinations with SHP2 and CDK inhibitors. She has contributed to understanding KRAS G12C inhibitor activity in brain metastases.

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🧪Research Fields 研究领域

KRAS G12C
Adagrasib
Preclinical development
Drug design
Combination strategies

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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