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Translational Medicine / 转化医学Cancer DNA Damage and Replication Stress
Thanos Halazonetis
MD, PhD
🏢University of Geneva🌐Switzerland
Professor of Molecular Biology
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Key Papers
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Key Contributions
👥Biography 个人简介
Thanos Halazonetis defined the concept of oncogene-induced replication stress as a driver of genome instability in early cancer. His laboratory has shown that replication stress activates the DNA damage response and drives selection for p53 loss. He is a leading figure in replication stress biology.
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🧪Research Fields 研究领域
replication stress
oncogene induced DNA damage
cancer genome instability
ATR signaling
common fragile sites
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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