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Translational Medicine / 转化医学Circulating Tumor Cell Technology

Daniel Haber

MD

🏢Massachusetts General Hospital / Harvard Medical School🌐USA

Director of Massachusetts General Hospital Cancer Center

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👥Biography 个人简介

Daniel Haber has pioneered the molecular characterization of circulating tumor cells, demonstrating that CTC genotyping can detect drug resistance mutations months before radiographic progression. His single-CTC RNA sequencing studies have revealed transcriptional heterogeneity among CTCs that predicts metastatic organotropism. He leads clinical studies using serial CTC analysis to guide adaptive therapy in non-small cell lung cancer and breast cancer.

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🧪Research Fields 研究领域

CTC molecular characterization
EGFR mutations in CTCs
Liquid biopsy for drug resistance
CTC RNA profiling
Real-time treatment monitoring

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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