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Translational Medicine / 转化医学Myelodysplastic Syndromes, MDS Therapy

Guillermo Garcia-Manero

MD

🏢University of Texas MD Anderson Cancer Center🌐USA

Professor; Chief, Section of MDS

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Key Contributions

👥Biography 个人简介

Guillermo Garcia-Manero leads the MDS program at MD Anderson and is one of the most productive clinical investigators in this field globally. His research has defined optimal use of hypomethylating agents azacitidine and decitabine in high-risk MDS and led to development of oral decitabine/cedazuridine. He has pioneered combination approaches including azacitidine plus venetoclax for higher-risk MDS and studies of novel agents targeting TP53-mutated disease. He has led dozens of clinical trials and trained numerous MDS investigators.

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🧪Research Fields 研究领域

azacitidine MDS
decitabine MDS
MDS hypomethylating agents
TP53-mutated MDS
MDS new drug development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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