Gregg Semenza
MD
Professor of Genetic Medicine
👥Biography 个人简介
Gregg Semenza shared the 2019 Nobel Prize for discovering HIF-1 alpha — the master transcriptional regulator of the hypoxic response. His discovery of HIF-1's role in regulating VEGF and other hypoxia-response genes in tumors has been foundational for understanding how cancers adapt to low oxygen and resist therapy. HIF-1 remains an active therapeutic target in multiple cancer types.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-02-01 | All information from publicly available academic sources
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