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Translational Medicine / 转化医学TCR-T Cell Therapy

Philip Greenberg

MD

🏢Fred Hutchinson Cancer Center🌐USA

Professor of Medicine and Immunology

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👥Biography 个人简介

Philip Greenberg is a pioneer in antigen-specific adoptive T cell therapy at Fred Hutchinson Cancer Center, having developed WT1-targeted TCR-T cell therapy for acute myeloid leukemia that has shown promising clinical activity in preventing post-transplant relapse. His four decades of work on understanding how T cells recognize and kill cancer cells has provided fundamental insights that inform modern TCR-T cell therapy design. He has made seminal contributions to the identification of tumor-associated antigens and the development of methods to generate antigen-specific T cells for clinical use.

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🧪Research Fields 研究领域

Antigen-specific T cell therapy
WT1-targeted TCR-T cells
Leukemia adoptive immunotherapy
T cell immunobiology
Minor histocompatibility antigen targeting

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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