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Translational Medicine / 转化医学Cancer DNA Damage and Replication Stress

Roger Greenberg

MD, PhD

🏢University of Pennsylvania🌐USA

J. Samuel Staub, M.D. Professor; Director, Basic Science, Basser Center for BRCA

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Key Contributions

👥Biography 个人简介

Roger Greenberg has defined mechanisms of BRCA1-mediated homologous recombination and the 53BP1 DNA damage response pathway. His work supports the rationale for PARP inhibitors and other DDR-targeted cancer therapies. He directs basic science at the Basser Center for BRCA.

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🧪Research Fields 研究领域

BRCA1 biology
homologous recombination
53BP1
DNA damage response
cancer synthetic lethality

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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