Giuseppe Viale
朱塞佩·维亚莱
MD, DiplSurg
Professor of Pathology and Chairman, Division of Pathology and Laboratory Medicine病理学教授兼主任，病理与实验医学部
👥Biography 个人简介
Internationally preeminent breast cancer pathologist and central reference pathologist for major global trials including BIG 1-98 and SOFT/TEXT. Spearheaded HER2 and Ki67 standardization for the St. Gallen International Breast Cancer Consensus, shaping worldwide pathology practice.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
HER2 and Ki67 International Standardization
Served as central pathology reference for multiple landmark international breast cancer trials, identifying sources of inter-laboratory variability in HER2 and Ki67 scoring and developing calibration tools adopted by the St. Gallen consensus panel.
St. Gallen Guideline Pathology Leadership
Long-serving member and pathology lead of the St. Gallen International Breast Cancer Conference Expert Panel, integrating pathologic biomarkers including intrinsic subtypes and Ki67 thresholds into consensus treatment recommendations.
Representative Works 代表性著作
Ki67 as a Prognostic and Predictive Biomarker in Breast Cancer: Lessons from the International Ki67 in Breast Cancer Working Group
JNCI: Journal of the National Cancer Institute (2022)
Summarized outcomes of multi-center Ki67 standardization efforts, establishing pre-analytical and analytical variables critical for reproducible scoring.
HER2 Status Reassessment in Primary and Metastatic Breast Cancer: Impact on Treatment Decisions
Annals of Oncology (2023)
Multi-center study revealing clinically significant HER2 status discordance between primary and metastatic sites, supporting rebiopsy at progression.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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