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Translational Medicine / 转化医学Breast Cancer

Giuseppe Curigliano

朱塞佩·库里格利亚诺

MD, PhD

🏢European Institute of Oncology (IEO), University of Milan(米兰欧洲肿瘤研究所)🌐Italy

Professor of Medical Oncology; Head, Early Drug Development Division肿瘤内科学教授;早期药物研发部主任

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Key Papers
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Key Contributions

👥Biography 个人简介

Internationally recognized breast oncologist at IEO Milan, leading early drug development and clinical trials in HER2+ breast cancer, immunotherapy combinations, and novel TKI strategies. Key contributor to ESMO breast cancer guidelines.

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🧪Research Fields 研究领域

Breast Cancer乳腺癌
HER2+ Breast CancerHER2阳性乳腺癌
Immunotherapy免疫治疗
HER2 TKIsHER2酪氨酸激酶抑制剂
Early Drug Development早期药物研发

🎓Key Contributions 主要贡献

HER2+ Breast Cancer & Immunotherapy

Conducted pivotal early-phase trials combining HER2-targeted TKIs with immunotherapy; contributed to ESMO guidelines shaping European breast cancer treatment standards and led multiple Phase I/II ADC studies.

Representative Works 代表性著作

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Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer (HER2CLIMB)

New England Journal of Medicine (2020)

Co-investigator on HER2CLIMB establishing tucatinib combination as standard in HER2+ MBC including brain metastases.

🏆Awards & Recognition 奖项与荣誉

🏆ESMO Distinguished Investigator Award
🏆AIRC Senior Investigator Grant

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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