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Translational Medicine / 转化医学DLBCL Molecular Classification, Novel Therapies

Gilles Salles

MD, PhD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Professor of Medicine; Chief, Lymphoma Service

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👥Biography 个人简介

Gilles Salles is a world-leading lymphoma clinician and researcher who has contributed to defining the molecular classification of DLBCL and led pivotal trials including POLARIX, which established polatuzumab vedotin plus R-CHP as superior to R-CHOP in first-line DLBCL. Previously at Hopital Lyon-Sud, his research covers B cell receptor signaling, obinutuzumab optimization, and novel treatment combinations. He is a co-author of major DLBCL treatment guidelines and has published more than 500 papers in hematologic oncology. His leadership of international lymphoma trial networks has shaped modern DLBCL management.

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🧪Research Fields 研究领域

DLBCL cell-of-origin GCB ABC subtype
obinutuzumab DLBCL follicular GALLIUM
polatuzumab vedotin DLBCL POLARIX
diffuse large B cell lymphoma molecular subtypes
CD20 antibody optimization lymphoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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