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Translational Medicine / 转化医学Allogeneic Cell Therapy

Saar Gill

MD, PhD

🏢University of Pennsylvania🌐USA

Associate Professor of Hematology-Oncology

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👥Biography 个人简介

Saar Gill is a leading researcher in allogeneic cell therapy approaches at the University of Pennsylvania, developing off-the-shelf CAR-T and CAR-NK cell products that can be manufactured from healthy donors and administered without HLA matching. His work on CRISPR-based gene editing to eliminate T cell receptor expression and HLA molecules from donor T cells has been pivotal in preventing graft-versus-host disease in allogeneic CAR-T products. He is advancing universal CAR-T platforms targeting myeloid malignancies where autologous approaches face manufacturing challenges.

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🧪Research Fields 研究领域

Allogeneic CAR-T development
CAR-NK cell therapy
Off-the-shelf cell products
Myeloid malignancy cell therapy
Gene editing for allogeneic cells

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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