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Translational Medicine / 转化医学TCR Bispecific, Melanoma

Gernot Stuhler

MD, PhD

🏢Deutsche Klinik fur Diagnostik🌐Germany

Professor of Hematology and Cell Therapy

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Key Contributions

👥Biography 个人简介

Dr. Gernot Stuhler is a hematologist and immunotherapy specialist who has contributed to the development and clinical evaluation of tebentafusp (IMCgp100), the first TCR bispecific T-cell engager to receive FDA approval for unresectable or metastatic uveal melanoma. He has investigated the unique biology of HLA-A*02:01-restricted T-cell engagement and the distinct mechanisms of action of TCR bispecifics compared to antibody-based engagers.

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🧪Research Fields 研究领域

tebentafusp HLA-A*02:01 gp100
TCR bispecific T-cell engager
uveal melanoma IMCgp100
HLA-restricted immunotherapy
ImmTAC platform

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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