Georgina Long
乔治娜·朗
MBBS, PhD
Co-Medical Director, Professor of Melanoma Medical Oncology联合医疗主任，黑色素瘤肿瘤内科学教授
👥Biography 个人简介
Georgina Long is co-medical director of Melanoma Institute Australia and a global leader in adjuvant and neoadjuvant immunotherapy for melanoma. Her landmark OpACIN and COMBI-AD trial contributions have transformed perioperative management and established Australia as a world center for melanoma research.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Neoadjuvant Immunotherapy
Led OpACIN and OpACIN-neo trials establishing neoadjuvant ipilimumab-nivolumab as highly active in stage III melanoma, achieving major pathologic responses and reshaping surgical planning.
Adjuvant Targeted Therapy
Contributed to COMBI-AD trial demonstrating that adjuvant dabrafenib-trametinib significantly reduces relapse risk in resected BRAF-mutant stage III melanoma.
Multidisciplinary Melanoma Care
Developed and disseminated multidisciplinary care models integrating surgery, immunotherapy, and targeted therapy, improving outcomes and reducing mortality across Australian cancer centers.
Representative Works 代表性著作
Neoadjuvant Ipilimumab and Nivolumab versus Standard-of-Care in Melanoma (OpACIN-neo)
The Lancet Oncology (2019)
Defined optimal dosing of neoadjuvant dual checkpoint blockade achieving high pathologic complete response in stage III melanoma.
Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma (COMBI-AD)
New England Journal of Medicine (2017)
Demonstrated 3-year relapse-free survival benefit of adjuvant BRAF/MEK inhibition, changing standard of care.
Five-Year Outcomes of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma
New England Journal of Medicine (2022)
Confirmed durable long-term RFS and OS benefit of adjuvant targeted therapy in BRAF-mutant melanoma.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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