Caroline Robert
卡罗琳·罗伯特
MD, PhD
Head of Dermatology Unit, Professor of Oncology皮肤科主任，肿瘤学教授
👥Biography 个人简介
Caroline Robert is Europe's foremost melanoma specialist, leading groundbreaking clinical trials of BRAF and MEK inhibitors at Institut Gustave Roussy. She has made defining contributions to targeted therapy and immunotherapy for melanoma, shaping European and global treatment guidelines.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
BRAF/MEK Targeted Therapy
Led pivotal European clinical trials of vemurafenib, dabrafenib, and trametinib in BRAF-mutated melanoma, establishing combined BRAF/MEK inhibition as standard of care.
Melanoma Immunotherapy
Conducted landmark pembrolizumab trials in advanced melanoma, demonstrating unprecedented durable responses and contributing to global regulatory approvals.
Melanoma Guidelines
Shaped ESMO clinical practice guidelines for advanced melanoma, integrating biomarker-driven treatment selection and combination therapy strategies across Europe.
Representative Works 代表性著作
Pembrolizumab versus Ipilimumab for Advanced Melanoma (KEYNOTE-006)
New England Journal of Medicine (2015)
Demonstrated pembrolizumab superiority over ipilimumab in overall survival and progression-free survival, redefining first-line melanoma treatment globally.
Nivolumab in Previously Untreated Melanoma without BRAF Mutation
New England Journal of Medicine (2015)
Established nivolumab as effective first-line therapy for BRAF wild-type advanced melanoma, expanding immunotherapy options.
Dabrafenib plus Trametinib versus Vemurafenib for BRAF V600E Melanoma
New England Journal of Medicine (2015)
Confirmed combined BRAF/MEK inhibition superiority over BRAF monotherapy, establishing doublet targeted therapy as standard of care.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
University of California, Los Angeles (UCLA)
Jedd Wolchok
Memorial Sloan Kettering Cancer Center / Weill Cornell Medicine
Keith Flaherty
Massachusetts General Hospital / Harvard Medical School
Alexander Eggermont
Princess Máxima Center / Institut Gustave Roussy
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