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Translational Medicine / 转化医学Melanoma Neoadjuvant Immunotherapy, Stage III Adjuvant

Georgina Long

MBBS, PhD

🏢Melanoma Institute Australia / University of Sydney🌐Australia

Co-Medical Director, Melanoma Institute Australia

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👥Biography 个人简介

Georgina Long has spearheaded neoadjuvant immunotherapy approaches for resectable high-risk stage III melanoma, demonstrating that presurgical combination checkpoint blockade achieves pathological complete responses in the majority of patients and may offer superior long-term outcomes compared to adjuvant-only strategies. Her NEONAX and NADINA trials have shaped understanding of neoadjuvant combination nivolumab plus ipilimumab in resectable stage III disease. She has investigated MRD monitoring through ctDNA surveillance as a tool to guide adjuvant therapy intensification or de-escalation after neoadjuvant treatment. Her leadership of Australia's melanoma clinical trial network has advanced international melanoma treatment standards.

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🧪Research Fields 研究领域

neoadjuvant melanoma immunotherapy
adjuvant BRAF MEK inhibitors
melanoma clinical trials Australia
pathological response melanoma
MRD ctDNA melanoma monitoring

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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