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Translational Medicine / 转化医学Melanoma Combination Immunotherapy, BRAF/MEK + IO

Georgina Long

MBBS, PhD

🏢Melanoma Institute Australia / University of Sydney🌐Australia

Co-Medical Director, Melanoma Institute Australia

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👥Biography 个人简介

Georgina Long is a world-leading investigator in melanoma treatment who has conducted landmark trials of combination immunotherapy and targeted therapy strategies. Her research has advanced ipilimumab plus nivolumab in the neoadjuvant setting for high-risk resectable melanoma, demonstrating that neoadjuvant combination checkpoint blockade achieves pathological complete responses in the majority of patients. She has investigated combinations of BRAF/MEK inhibitors with immunotherapy in BRAF-mutated melanoma. Her contributions to adjuvant immunotherapy trials established pembrolizumab, nivolumab, and BRAF/MEK inhibitor combination as standard adjuvant regimens for resected high-risk melanoma. Her clinical research has fundamentally shaped current melanoma treatment paradigms.

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🧪Research Fields 研究领域

melanoma immunotherapy
BRAF/MEK inhibitors melanoma
targeted therapy immunotherapy combination
adjuvant melanoma
neoadjuvant melanoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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