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Translational Medicine / 转化医学Cascade Testing, BRCA Functional Analysis

Georgia Chenevix-Trench

PhD, FRCPA

🏢QIMR Berghofer Medical Research Institute🌐Australia

Head, Cancer Genetics Laboratory

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👥Biography 个人简介

Georgia Chenevix-Trench leads the ENIGMA international consortium for classification of variants in hereditary cancer genes, particularly BRCA1 and BRCA2. She has developed multifactorial likelihood models for variant classification and coordinated international data sharing to reclassify thousands of VUS. Her work has been fundamental to improving the clinical utility of hereditary cancer genetic testing globally.

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🧪Research Fields 研究领域

cascade testing hereditary cancer
BRCA functional assay classification
ENIGMA consortium VUS
hereditary cancer genetics Australia
BRCA variant reclassification

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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