Georg Bhatt

Georg Bhatt is a leading researcher in mechanotransduction and its regulation of the Hippo-YAP pathway in cancer. His research has established how extracellular matrix stiffness and mechanical forces activate YAP/TAZ to promote cancer cell growth and invasion. He has characterized specific cytoskeletal and integrin-mediated signals that relay mechanical inputs to the Hippo kinase cascade. His work connects the tumor mechanical microenvironment to transcriptional programs driven by YAP/TAZ.