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Translational Medicine / 转化医学LNP Intracellular Trafficking, mRNA Delivery

Gaurav Sahay

PhD

🏢Oregon State University / Oregon Health & Science University🌐USA

Associate Professor, Department of Pharmaceutical Sciences

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Key Contributions

👥Biography 个人简介

Dr. Gaurav Sahay is an expert in lipid nanoparticle intracellular trafficking who has revealed the mechanisms by which LNPs escape endosomes to deliver mRNA therapeutics. His research has defined how LNP formulation affects endosomal escape efficiency -- a critical bottleneck in mRNA cancer vaccine delivery. His work has directly informed the design of next-generation LNP systems for cancer mRNA therapeutics.

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🧪Research Fields 研究领域

endosomal escape LNP
mRNA cancer vaccines
LNP cellular uptake
ionizable lipid design
nanoparticle tumor delivery

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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