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Translational Medicine / 转化医学ctDNA Real-Time Therapy Monitoring

Isaac Garcia-Murillas

PhD

🏢Institute of Cancer Research London🌐UK

Team Leader in Molecular Oncology

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Key Contributions

👥Biography 个人简介

Isaac Garcia-Murillas has been instrumental in developing personalized ctDNA tracking assays for monitoring treatment response and detecting minimal residual disease in breast cancer, demonstrating that ctDNA detection after neoadjuvant chemotherapy predicts relapse with high specificity months before clinical recurrence. His research at the Institute of Cancer Research has established the clinical utility of serial ctDNA monitoring for real-time assessment of therapy effectiveness in early-stage breast cancer. His work has been foundational in establishing ctDNA as a tool for treatment adaptation and early intervention in breast cancer management.

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🧪Research Fields 研究领域

ctDNA breast cancer recurrence
Minimal residual disease ctDNA
Personalized ctDNA tracking
Neoadjuvant therapy ctDNA monitoring
Mutation tracking serial ctDNA

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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