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Translational Medicine / 转化医学Infection-Associated Cancer in Tropical/LMICs

Donald Ganem

MD

🏢University of California San Francisco / Novartis Institutes🌐USA

Professor of Microbiology and Medicine

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👥Biography 个人简介

Donald Ganem is a leading virologist whose work on Kaposi sarcoma-associated herpesvirus (KSHV/HHV-8) elucidated the molecular mechanisms by which this virus causes Kaposi sarcoma and primary effusion lymphoma, cancers predominantly affecting immunocompromised populations in tropical and sub-Saharan African settings. His characterization of KSHV latent and lytic gene products that drive cell proliferation and angiogenesis has been foundational for understanding viral oncogenesis. His research has informed treatment strategies for AIDS-associated malignancies worldwide.

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🧪Research Fields 研究领域

KSHV/HHV-8 virology
Kaposi sarcoma molecular biology
Viral oncogenesis mechanisms
Primary effusion lymphoma
AIDS-associated malignancies

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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