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Translational Medicine / 转化医学Adaptive Therapy and Evolutionary Strategy

Jill Gallaher

PhD

🏢Moffitt Cancer Center🌐USA

Research Scientist, Integrated Mathematical Oncology

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👥Biography 个人简介

Jill Gallaher develops spatial agent-based computational models of tumor evolution under adaptive therapy, demonstrating that the spatial structure of tumors critically influences the effectiveness of competition-mediated resistance suppression and identifying optimal dosing schedules that maximize competitive suppression of resistant clones. Her research at Moffitt Cancer Center has shown that spatial modeling captures dynamics missed by non-spatial models and that tumor geometry and cell mixing patterns determine whether adaptive therapy can achieve durable disease control. Her computational work provides the quantitative foundation for designing patient-specific adaptive therapy protocols.

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🧪Research Fields 研究领域

Spatial tumor modeling
Agent-based cancer simulation
Adaptive therapy optimization
Spatial competition resistant cells
Computational evolutionary oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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