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Translational Medicine / 转化医学ROS1 Fusion Resistance Mechanisms

Justin Gainor

MD

🏢Massachusetts General Hospital🌐USA

Director, Center for Thoracic Cancers

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Key Contributions

👥Biography 个人简介

Justin Gainor directs the Center for Thoracic Cancers at Mass General and has published seminal work on immunotherapy resistance in ROS1-positive NSCLC. His research demonstrated that ALK and ROS1-rearranged tumors have low PD-L1 expression and poor immunotherapy response. He has contributed to rational combination strategies for this population.

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🧪Research Fields 研究领域

ROS1 fusions
Immunotherapy resistance
ALK-positive NSCLC
Biomarker research
Translational oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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