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Translational Medicine / 转化医学MDSCs, Tumor Immunosuppression

Dmitry Gabrilovich

MD, PhD

🏢AstraZeneca🌐USA

Vice President, Chief Scientific Officer

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Key Contributions

👥Biography 个人简介

Dmitry Gabrilovich is the pioneer who defined myeloid-derived suppressor cells (MDSCs) as a major mechanism of tumor immune evasion. His foundational work established that MDSCs accumulate in cancer patients and suppress T cell responses through multiple molecular mechanisms. He has published over 200 papers on MDSC biology and therapeutic strategies to deplete or reprogram these cells to enhance immunotherapy. His research is foundational to understanding myeloid immunosuppression in cancer.

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🧪Research Fields 研究领域

myeloid-derived suppressor cells
tumor immunosuppression
immunotherapy
cancer vaccines
innate immunity

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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