Franklin Huang
MD, PhD
Associate Professor of Medicine
👥Biography 个人简介
Franklin Huang discovered the mechanism by which TERT promoter mutations (C228T and C250T) activate telomerase expression in cancer. His work revealed that these mutations create de novo binding sites for the GABP transcription factor, explaining how the most common non-coding mutations in cancer reactivate telomerase. These findings opened new therapeutic strategies targeting TERT promoter-driven transcription in glioblastoma and melanoma.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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