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Translational Medicine / 转化医学Let-7 microRNA, Cancer Therapy

Frank Slack

PhD

🏢Beth Israel Deaconess / Harvard🌐USA

Director, Institute for RNA Medicine

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Key Contributions

👥Biography 个人简介

Frank Slack has made major contributions to understanding let-7 microRNA as a tumor suppressor and to translating miRNA biology into cancer therapy. His work demonstrating that let-7 loss promotes lung and other cancers, and his development of miRNA replacement and inhibition strategies as cancer therapeutics, has been important for the RNA therapeutics oncology field.

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🧪Research Fields 研究领域

let-7 tumor suppressor miRNA
miRNA cancer therapy
miRNA replacement cancer
oncomiR targeting
miR-21 cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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