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Translational Medicine / 转化医学Gastric Cancer, CLDN18.2 and Zolbetuximab

Florian Lordick

MD

🏢University of Leipzig🌐Germany

Professor of Oncology, Director of University Cancer Center

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👥Biography 个人简介

Florian Lordick at the University of Leipzig has been central to European gastric cancer research including work on CLDN18.2 as a therapeutic target. He was involved in the SPOTLIGHT and GLOW trials that established zolbetuximab plus chemotherapy as a new standard for CLDN18.2-positive HER2-negative advanced gastric cancer. His research has contributed to the molecular characterization of gastric cancer and the identification of actionable targets beyond HER2. He has led ESMO and German AIO clinical guideline development for gastric cancer and has been a key figure in European GI oncology.

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🧪Research Fields 研究领域

zolbetuximab CLDN18.2 gastric
SPOTLIGHT GLOW trials gastric
CLDN18.2 expression gastric cancer
gastric cancer targeted therapy Europe
biomarker-selected gastric therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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