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Translational Medicine / 转化医学Ovarian Cancer, PARP Resistance
Fiona Simpkins
MD
🏢University of Pennsylvania🌐USA
Associate Professor of Gynecologic Oncology
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Key Contributions
👥Biography 个人简介
Fiona Simpkins runs a translational ovarian cancer program focused on PARP inhibitor resistance mechanisms using patient-derived xenografts and organoids. She has led early-phase trials combining PARP inhibitors with ATR and WEE1 inhibitors. Her work informs next-generation DDR strategies.
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🧪Research Fields 研究领域
PARP resistance PDX models
ATR inhibitors
combination DDR strategies
BRCA reversion
translational ovarian research
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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