Rainer Fietkau

Rainer Fietkau leads clinical trials combining regional hyperthermia with radiation therapy and chemotherapy for locally advanced rectal and cervical cancers, demonstrating significant improvements in complete pathological response rates. His radiothermotherapy protocols have established temperature thresholds and heating durations needed for optimal radiosensitization in clinical settings. He has contributed to European guidelines for hyperthermia quality assurance in multi-institutional clinical trials.