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Translational Medicine / 转化医学Oncology Regulatory Science

Ezekiel Emanuel

以西结·伊曼纽尔

MD, PhD

🏢University of Pennsylvania(宾夕法尼亚大学)🌐USA

Vice Provost for Global Initiatives; Diane v.S. Levy and Robert M. Levy University Professor全球事务副教务长;列维讲席大学教授

72
h-index
3
Key Papers
3
Awards
3
Key Contributions

👥Biography 个人简介

Ezekiel Emanuel is one of the world's foremost bioethicists, with seminal contributions to clinical trial ethics, informed consent, and oncology research policy. He has shaped both U.S. and international frameworks governing the ethical conduct of cancer clinical trials and drug development.

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🧪Research Fields 研究领域

Clinical Trial Ethics临床试验伦理
Informed Consent知情同意
Oncology Policy肿瘤政策
Research Ethics研究伦理

🎓Key Contributions 主要贡献

Ethical Framework for Clinical Research

Developed the widely-adopted seven-requirement framework for ethical clinical research that guides IRB review and trial conduct globally in oncology and beyond.

Informed Consent Reform

Produced landmark empirical and normative research on informed consent in oncology trials, revealing failures and proposing evidence-based improvements.

Oncology Drug Pricing and Access Ethics

Authored influential analyses of ethical dimensions of cancer drug pricing, access inequality, and value-based regulatory frameworks.

Representative Works 代表性著作

[1]

What Makes Clinical Research Ethical?

Journal of the American Medical Association (2000)

Landmark paper proposing a systematic seven-requirement framework for evaluating the ethics of clinical research, widely cited in oncology and other fields.

[2]

Informed Consent for Cancer Clinical Trials: A Review

Journal of Clinical Oncology (2004)

Comprehensive empirical and ethical review of consent practices in cancer trials, identifying persistent gaps in patient understanding.

[3]

The Costs of Cancer Care and the Ethics of Oncology Drug Pricing

JAMA Oncology (2016)

Argued for ethical obligations of pharmaceutical companies in pricing cancer drugs and proposed regulatory policy remedies.

🏆Awards & Recognition 奖项与荣誉

🏆Hastings Center Distinguished Fellow
🏆American College of Physicians (ACP) Laureate Award
🏆Presidential Commission for the Study of Bioethical Issues Member

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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