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Translational Medicine / 转化医学Leukemia, IDH1/IDH2 Inhibitors

Eytan Stein

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Associate Attending, Leukemia Service

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Key Contributions

👥Biography 个人简介

Eytan Stein is a leading expert in IDH-mutated AML and has been a principal investigator on pivotal trials for both enasidenib (IDH2 inhibitor) and ivosidenib (IDH1 inhibitor). His work has defined the clinical activity and toxicity profile of IDH inhibitors, including the critical management of differentiation syndrome. He has contributed to understanding IDH inhibitor resistance and rational combination strategies.

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🧪Research Fields 研究领域

IDH1 inhibitors AML
IDH2 inhibitors AML
enasidenib
ivosidenib
differentiation syndrome AML

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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