Eric Winer
MD
Director, Yale Cancer Center; Professor, Yale School of Medicine; Former Chief, Division of Breast Oncology, Dana-Farber
👥Biography 个人简介
Eric Winer is Director of the Yale Cancer Center and one of the most influential clinical leaders in breast oncology. Over a distinguished career spanning Dana-Farber Cancer Institute and now Yale, he has shaped breast cancer clinical research through his scientific contributions and his leadership of the Alliance for Clinical Trials in Oncology and other national cooperative groups. His research interests have particularly centered on triple-negative breast cancer, a historically difficult-to-treat subtype, and on integrating immunotherapy into breast cancer regimens. Winer has contributed to pivotal studies evaluating immune checkpoint inhibitors in TNBC, including pembrolizumab and atezolizumab combinations with chemotherapy, which have led to FDA approvals in PD-L1-positive TNBC. He has also championed the study of olaparib and other PARP inhibitors in BRCA-mutated breast cancer, and has long been a voice for ensuring that clinical trials reflect the diversity of the patient population, particularly in terms of race and ethnicity. Beyond his scientific output, Winer has helped define quality measures in breast cancer care and has worked to improve care delivery in community settings. He is known as an exceptional mentor and has trained many of today's leading breast oncologists. His transition to lead Yale Cancer Center reflects the broad trust the oncology community places in his leadership and scientific vision.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Immunotherapy Integration in TNBC
Contributed to the clinical development of immune checkpoint inhibitor combinations in TNBC, helping establish pembrolizumab plus chemotherapy as a standard of care in early-stage and metastatic PD-L1-positive TNBC through trials including KEYNOTE-522.
PARP Inhibitors in BRCA-Mutated Breast Cancer
Supported and contributed to clinical evaluation of olaparib and talazoparib in germline BRCA1/2-mutated HER2-negative metastatic breast cancer, leading to approvals expanding treatment options for hereditary breast cancer.
Clinical Trials Leadership and Cooperative Group Science
Served in leadership roles in the Alliance for Clinical Trials in Oncology and other national groups, designing pivotal breast cancer trials and ensuring rigorous scientific standards and broad patient access.
Health Disparities and Diversity in Oncology
Advocated for and studied racial and socioeconomic disparities in breast cancer outcomes and clinical trial participation, working to improve equity in cancer care and research.
Representative Works 代表性著作
Pembrolizumab for Early Triple-Negative Breast Cancer (KEYNOTE-522)
New England Journal of Medicine (2020)
Demonstrated that adding pembrolizumab to neoadjuvant chemotherapy significantly improved pathologic complete response rates in early TNBC.
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation (OlympiAD)
New England Journal of Medicine (2017)
Pivotal trial establishing olaparib as a treatment for BRCA-mutated, HER2-negative metastatic breast cancer with significant PFS benefit over standard chemotherapy.
Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation (EMBRACA)
New England Journal of Medicine (2018)
Confirmed PARP inhibitor benefit in BRCA-mutated breast cancer with talazoparib, showing improved PFS and quality of life over chemotherapy.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-04-05 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
关注 Eric Winer 的研究动态
Follow Eric Winer's research updates
留下邮箱,当我们发布与 Eric Winer(Yale Cancer Center / Dana-Farber Cancer Institute)相关的新研究或访谈时,我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment