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Translational Medicine / 转化医学AR Splice Variants, CRPC Biology

Eric Small

MD

🏢UC San Francisco🌐USA

Professor and Chief

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Key Contributions

👥Biography 个人简介

Eric Small at UCSF has contributed to understanding androgen receptor (AR) biology in CRPC, including the clinical importance of AR splice variants (particularly AR-V7) as mechanisms of resistance to enzalutamide and abiraterone. His work on AR-V7 detection in circulating tumor cells as a predictive biomarker for second-generation AR inhibitor therapy has important implications for treatment sequencing in CRPC.

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🧪Research Fields 研究领域

AR-V7 splice variant resistance
androgen receptor splice variants CRPC
abiraterone enzalutamide resistance
AR splice CRPC biology
prostate cancer precision oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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