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Translational Medicine / 转化医学Ovarian Cancer

Eric Pujade-Lauraine

埃里克·普雅德-劳兰

MD, PhD

🏢Université Paris Cité (Paris Descartes) / ARCAGY-GINECO(巴黎西岱大学(巴黎笛卡尔)/ARCAGY-GINECO研究组)🌐France

Professor of Medical Oncology (Emeritus); Chair, ARCAGY-GINECO Cooperative Group肿瘤内科学荣誉教授;ARCAGY-GINECO合作组主席

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Eric Pujade-Lauraine, MD, PhD is an Emeritus Professor at Université Paris Cité and longtime Chair of ARCAGY-GINECO, France's leading gynecologic oncology cooperative group. He led the ICON6 trial of cediranib and multiple bevacizumab pivotal trials, shaping anti-angiogenic treatment standards for ovarian cancer worldwide.

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🧪Research Fields 研究领域

Ovarian Cancer卵巢癌
Bevacizumab贝伐珠单抗
Anti-Angiogenic Therapy抗血管生成治疗
Cediranib西地尼布
Platinum-Resistant Ovarian Cancer铂耐药卵巢癌

🎓Key Contributions 主要贡献

Bevacizumab in Platinum-Resistant Ovarian Cancer (AURELIA Trial)

Led the AURELIA trial demonstrating that adding bevacizumab to chemotherapy significantly improved progression-free survival and response rates in platinum-resistant ovarian cancer, establishing bevacizumab as standard in this setting.

ICON6 Cediranib Trial

Contributed to the ICON6 phase III trial evaluating cediranib (VEGFR inhibitor) in platinum-sensitive recurrent ovarian cancer, providing key insights into maintenance anti-angiogenic strategies.

Representative Works 代表性著作

[1]

Bevacizumab in patients with platinum-resistant, recurrent ovarian cancer (AURELIA)

Journal of Clinical Oncology (2014)

Phase III trial establishing bevacizumab plus chemotherapy as standard care in platinum-resistant recurrent ovarian cancer, nearly doubling response rate.

[2]

Cediranib with and without olaparib versus standard platinum-based chemotherapy in recurrent platinum-sensitive ovarian cancer (ICON6)

The Lancet (2021)

Phase III trial evaluating cediranib combinations in platinum-sensitive recurrent ovarian cancer, clarifying the role of VEGFR inhibition in maintenance strategies.

🏆Awards & Recognition 奖项与荣誉

🏆European Society of Gynaecological Oncology Honorary Membership
🏆GCIG Lifetime Achievement Award
🏆Ligue Nationale Contre le Cancer Distinguished Investigator Prize

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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