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Translational Medicine / 转化医学Adrenal & Rare Endocrine Cancers

Eric Baudin

埃里克·鲍丁

MD, PhD

🏢Institut Gustave Roussy(古斯塔夫·鲁西研究所)🌐France

Professor and Head of Endocrine Oncology内分泌肿瘤科主任教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Eric Baudin leads the endocrine oncology program at Institut Gustave Roussy, directing seminal trials for malignant pheochromocytoma, paraganglioma, and adrenocortical carcinoma. He coordinated the FIRSTMAPPP trial of sunitinib in malignant PPGL and has pioneered peptide receptor radionuclide therapy in these rare tumors.

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🧪Research Fields 研究领域

Pheochromocytoma Systemic Therapy嗜铬细胞瘤系统治疗
Malignant PPGL恶性副神经节瘤
Targeted Therapies for Endocrine Tumors内分泌肿瘤靶向治疗

🎓Key Contributions 主要贡献

FIRSTMAPPP Trial

Led the first randomized controlled trial (FIRSTMAPPP) of sunitinib in progressive malignant PPGL, demonstrating progression-free survival benefit and establishing a new treatment standard.

PRRT in Malignant PPGL

Advanced the evidence base for peptide receptor radionuclide therapy with 177Lu-DOTATATE in somatostatin receptor-expressing malignant pheochromocytoma and paraganglioma.

European PPGL Treatment Guidelines

Co-authored European Society of Endocrinology guidelines for malignant PPGL, integrating systemic therapy options and providing the first structured treatment algorithm.

Representative Works 代表性著作

[1]

Sunitinib in Patients with Progressive Malignant Pheochromocytoma or Paraganglioma (FIRSTMAPPP)

Annals of Oncology (2021)

Phase II RCT demonstrating significant improvement in progression-free survival with sunitinib in malignant PPGL, supporting its use as standard therapy.

[2]

Malignant Pheochromocytoma/Paraganglioma: Management with Chemotherapy and New Targeted Therapies

Best Practice & Research Clinical Endocrinology & Metabolism (2020)

Comprehensive review of systemic treatment options for malignant PPGL including chemotherapy, targeted agents, and radionuclide therapy.

[3]

European Society of Endocrinology Clinical Practice Guideline for Long-Term Follow-Up of Patients Operated on for a Phaeochromocytoma or a Paraganglioma

European Journal of Endocrinology (2016)

Guideline establishing risk-stratified long-term surveillance protocols after PPGL surgery.

🏆Awards & Recognition 奖项与荣誉

🏆French National Cancer Institute Excellence Award
🏆European Neuroendocrine Tumor Society Research Prize

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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