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Translational Medicine / 转化医学Ovarian Cancer, HRD and Reversion

Elizabeth Swisher

MD

🏢University of Washington / Fred Hutch🌐USA

Professor of Gynecologic Oncology

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Key Papers
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Key Contributions

👥Biography 个人简介

Elizabeth Swisher identified BRCA reversion mutations as a mechanism of PARP inhibitor resistance and led the biomarker work for ARIEL2 defining the rucaparib HRD LOH signature. Her laboratory continues to characterize homologous recombination repair defects. She runs an active ovarian cancer prevention clinic.

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🧪Research Fields 研究领域

BRCA reversion mutations
HRD genomics
ARIEL2 biomarker
LOH HRD signature
PARP resistance

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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